Sialidase testing panel (procainamide labelled)
Sialidase testing panel (procainamide labelled)
- Product Code: CPROC-STP-NEUAC-01
- Size 20 pmol
- £120
The Sialidase Testing Panel contains a mixture of α2-3, α2-6, and α2-8 sialylated oligosaccharides labelled with either 2-AB or procainamide. They were developed as a process control for sialidase digestions. Applied alongside the samples, it demonstratesshows that the enzymes have the expected specificity.
*New Product (size: 20 pmol)
Sialidase Testing Panel includes a mixture of five glycans:
- 3′-Sialyl Lewis X [Neu5Ac-a2-3Gal-b1-4(Fuc-a1-3)GlcNAc] – contains α2-3 linked sialic acid along with branched α1-3 fucose (introducing steric hindrance for some enzymatic reactions)
- Sialyllacto-N-tetraose a [Neu5Ac-α2-3Gal-β1-3GlcNAc-β1-3Gal-β1-4Glc] – linear oligosaccharide containing α2-3 sialic acid attached to galactose
- Disialyllactose [Neu5Ac-a2-8NeuAc-a2-3Gal-b1-4Glc] – linear oligosaccharide containing α2-8 linked sialic acid
- Sialyllacto-N-tetraose c [Neu5Ac-a2-6Gal-b1-4GlcNAc-b1-3Gal-b1-4Glc] – linear oligosaccharide containing α2-6 sialic acid attached to galactose
- Disialyllacto-N-tetraose [Neu5Ac-a2-3Gal-b1-3(Neu5Ac-a2-6)GlcNAc-b1-3Gal-b1-4Glc] – branched sialic acid oligosaccharide
Product Specifications
Sialidase Testing Panel – Procainamide Labelled Glycan Standard
The Sialidase Testing Panel contains a mixture of α2-3, α2-6, and α2-8 sialylated oligosaccharides labelled with either 2-AB or procainamide. They were developed as a process control for sialidase digestions. Applied alongside the samples, it demonstratesshows that the enzymes have the expected specificity.
Form: Dry. Dried by centrifugal evaporation from an aqueous solution.
Size: 20 pmol
Description: Sialidase Testing Panel includes a mixture of five glycans:
- 3′-Sialyl Lewis X [Neu5Ac-a2-3Gal-b1-4(Fuc-a1-3)GlcNAc] – contains α2-3 linked sialic acid along with branched α1-3 fucose (introducing steric hindrance for some enzymatic reactions)
- Sialyllacto-N-tetraose a [Neu5Ac-α2-3Gal-β1-3GlcNAc-β1-3Gal-β1-4Glc] – linear oligosaccharide containing α2-3 sialic acid attached to galactose
- Disialyllactose [Neu5Ac-a2-8NeuAc-a2-3Gal-b1-4Glc] – linear oligosaccharide containing α2-8 linked sialic acid
- Sialyllacto-N-tetraose c [Neu5Ac-a2-6Gal-b1-4GlcNAc-b1-3Gal-b1-4Glc] – linear oligosaccharide containing α2-6 sialic acid attached to galactose
- Disialyllacto-N-tetraose [Neu5Ac-a2-3Gal-b1-3(Neu5Ac-a2-6)GlcNAc-b1-3Gal-b1-4Glc] – branched sialic acid oligosaccharide
Molecular weight
- 3’-Sialyl Lewis X 940.3648
- Sialyllacto-N-tetraose a 1118.4126
- Disialyllactose 1044.3758
- Sialyllacto-N-tetraose c 1118.4126
- Disialyllacto-N-tetraose 1409.5080
Purity: 89% pure as assessed by UHPLC.
Storage : Store at -20°C both before and after dissolution. This product is stable for at least 5 years as supplied.
Shipping: The product can be shipped at ambient when dry. After dissolution, ship on dry ice.
Handling: Allow the unopened vial to reach ambient temperature. Centrifuge to ensure that most of the lyophilized material is at the bottom of the vial. Add the desired volume of reconstitution medium, re-cap and mix thoroughly to bring all the oligosaccharide into solution. Ensure that any glass, plasticware or solvents used are free of glycosidases and environmental carbohydrates.
Example use Sialidase Testing Panel can be used as process positive control for sialidase digestions. Applied alongside the samples, it enables to test if the sialidase used has required specificity and if it had worked correctly.
Warranties and liabilities
Ludger warrants that the above product conforms to the attached analytical documents. Should the product fail for reasons other than through misuse Ludger will, at its option, replace free of charge or refund the purchase price. This warranty is exclusive and Ludger makes no other warrants, expressed or implied, including any implied conditions or warranties of merchantability or fitness for any particular purpose. Ludger shall not be liable for any incidental, consequential or contingent damages. This product is intended for in vitro research only. Not for human or drug use.